Studying the functional conservation of cis-regulatory modules and their transcriptional output
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولComputational detection of cis-regulatory modules
MOTIVATION The transcriptional regulation of a metazoan gene depends on the cooperative action of multiple transcription factors that bind to cis-regulatory modules (CRMs) located in the neighborhood of the gene. By integrating multiple signals, CRMs confer an organism specific spatial and temporal rate of transcription. RESULTS Based on the hypothesis that genes that are needed in exactly th...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2008
ISSN: 1471-2105
DOI: 10.1186/1471-2105-9-220